The objective of project AMATHO is to develop a novel tiltrotor main drive system housing produced by additive manufacturing (AM) technology. Such a development process will include evaluation and choice of viable production processes and precursor materials; testing of coupons and intermediate proofs of concept for assessing static performance and fatigue endurance; design for manufacturing, definition of optimized manufacturing process, experimental testing and industrial engineering of an appropriate number of full scale housings to support flight clearance on NextGenCTR demonstrator. The adoption of suitable numerical tools for design, optimization and structural substantiation of the AM housing will constitute part of the project’s activities as well.